![]() ![]() Suppression in lung defense responses after bacterial infection in rats pretreated with different welding fumes.Īntonini, James M Taylor, Michael D Millecchia, Lyndell Bebout, Alicia R Roberts, Jenny RĮpidemiology suggests that inhalation of welding fumes increases the susceptibility to lung infection. At day 3, the rats were intratracheally inoculated with 5 x 10 and IL-6) after infection, which are On day 0, male Sprague-Dawley rats weremore » intratracheally instilled with saline (vehicle control) or the different welding fumes (0.1 or 2 mg/rat). The GMA-SS and GMA-MS fumes were found to be relatively insoluble, whereas the MMA-SS was highly water soluble, with the soluble fraction comprised of 87% Cr and 11% Mn. The fumes were separated into water-soluble and -insoluble fractions. #Mical se burla de david manualFume was collected during gas metal arc (GMA) or flux-covered manual metal arc (MMA) welding using two consumable electrodes: stainless steel (SS) or mild steel (MS). The effects of chemically distinct welding fumes on lung defense responses after bacterial infection were compared. Millecchia, LyndellĮpidemiology suggests that inhalation of welding fumes increases the susceptibility to lung infection. Suppression in lung defense responses after bacterial infection in rats pretreated with different welding fumesĪntonini, James M. Fatal consequences can be avoided with an appropriate prophylactic antibiotic regimen that must be modified according to the microorganisms isolated from cultures of samples obtained from donors, grafts, preservation fluids and recipients. Donor-to-host transmission of infection is a frequent event after lung transplantation. Excluding the five cases without an effective prophylactic regimen, prophylaxis failure occurred in 11 out of 197 procedures (5.58%). Twenty-five percent of donors with bacteremia and 14.1% of colonized grafts were responsible for transmitting infection. Among these cases, 2 were due to donor bacteremia and 13 to colonization of the graft. Donor-to-host transmission of bacterial or fungal infection occurred in 15 lung allograft recipients, 7.6% of lung transplants performed. Types of donor infection included isolated contamination of preservation fluids (n = 30, 29.1%), graft colonization (n = 65, 63.1%) and bacteremia (n = 8, 7.8%). The overall incidence of donor infection was 52% (103 out of 197 donors). Recipients who survived more than 24 h and their respective donors were evaluated. ![]() The purpose of this study was to evaluate the incidence and etiology of bacterial and fungal infection or contamination in lung allograft donors and to assess donor-to-host transmission of these infections. Ruiz, I Gavaldà , J Monforte, V Len, O Román, A Bravo, C Ferrer, A Tenorio, L Román, F Maestre, J Molina, I Morell, F Pahissa, A Donor-to-host transmission of bacterial and fungal infections in lung transplantation. ![]()
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